12/7/2023 0 Comments My favorite chaperone essayOutside of England, the primary person to bring attention to James Parkinson’s contribution was Jean-Martin Charcot, the premier 19th-century clinical neurologist. 11 Modern historians have reported on the wide reference to the work in England during the first decades after Parkinson’s publication, 12 documenting that some cases mimicked the disorder that Parkinson described, but others were more likely mistaken examples of other conditions. The Essay was acknowledged in the medical community, and multiple reviews praised the work, 10 including a compliment admiring Parkinson’s “characteristic modesty and the acuteness of his observation” (p. 63 see next section for further details). He did not specifically account for bradykinesia or rigidity, and in line with the term palsy, he considered the patients to be weak, although he acknowledged that the impairment “depends not on general weakness, but merely on the interruption of the flow of the nervous influence to the affected parts” (p. He described rest tremor, flexed posture, and festination. 9 As a highly astute observer, Parkinson described a disease of insidious onset and a progressive, disabling course. Admitting the paucity of information, both past and present, Parkinson aimed to present his “opinions to the examination of others, even in their present state of immaturity and imperfection” (p. 9 In this 5-chapter, 66-page monograph, he considered the historical background of the condition he was describing, its signs and symptoms, individual case observations on 6 subjects, differential diagnosis, etiology, and contemporary treatment. Regarding the topic of key interest to this article, Parkinson published An Essay on the Shaking Palsy in 1817. 8 His name is remembered in the classification of fossils, including the Nautilus parkinsoni and the Nipa parkinsoni. He was a founding member of the Geological Society and wrote several treatises on fossils, including the 3-volume Organic Remains of a Former World. 7 Outside of the realms of medicine and public health, James Parkinson was celebrated during his life for his geological and paleontological expertise. 4 More focused medical texts included an early essay on the effects of lightning 5 and later treatises on gout 6 and typhoid fever. Using his own name, he authored a number of very successful and respected books for the public on health and safety precautions, among them The Villager’s Friend and Physician 3 and the fully illustrated children’s book on safety titled Dangerous Sports. He was a political activist of his era and wrote several pamphlets on social and governmental reform efforts under the pseudonym of Old Hubert. Parkinson was a prolific author, and the topics of his publications were highly varied. It is also our deepest hope that this article will inspire the next generation of movement disorders clinicians and researchers to continue on this journey until we have reached our ultimate goal of defining the cause and finding the cure for PD.Ĭurrent picture of the house where James Parkinson lived and worked in East London and the commemorative plaque. Nevertheless, we believe this article represents a state-of-the-art account of PD and will serve to remind us of how much has been accomplished and how much more remains to be done. For obvious reasons, the article reflects differences in styles and diverse viewpoints. For the present article, a large number of esteemed colleagues dedicated to the study and advancement of movement disorders research summarize the hallmark advances that have taken place during the past 2 centuries in defining, understanding, and treating Parkinson’s disease (PD). With this article, the journal Movement Disorders commemorates the second centenary of the publication of the shaking palsy and joins several events organized by the International Parkinson’s Disease and Movement Disorders Society for this year.
0 Comments
Leave a Reply. |
AuthorWrite something about yourself. No need to be fancy, just an overview. ArchivesCategories |